Kamal OrthoGain

Introducing

OrthoGain

Regenerate. Restore. Relieve.

India's first autologous exosome kit

India's first autologous exosome kit enriched with growth factor concentrate represents a breakthrough in regenerative medicine — combining autologous exosomes with platelet-derived growth factors (GFs) to accelerate healing, reduce inflammation, and restore mobility naturally.

CDSCO Approved Clinically Proven Autologous & Safe

Exosomes — nature's nanocarriers

Biological messengers, delivered
where the tissue is failing

Exosomes are nanosized "biological messengers" released by cells. Rich in proteins, lipids, and genetic material, they deliver vital healing signals that promote repair and regeneration at the cellular level.

Key growth factors in OrthoGain™

PDGF
99443.75pg/ml
VEGF
3899pg/ml
EGF
550pg/ml
TGF-beta
1732.50pg/ml
bFGF
2793pg/ml

ELISA analysis verifies OrthoGain's elevated levels of PDGF, VEGF, EGF, and TGF-β, ensuring strong therapeutic activity. Consistent biomarker enrichment supports faster healing, improved outcomes, and better patient satisfaction.

The synergy of OrthoGain™. By combining autologous exosomes (loaded with mRNA & proteins) and concentrated growth factors, OrthoGain™ delivers a pioneering regenerative solution for orthopaedics and sports medicine.

Mechanism

Direct exosome-mediated
cellular communication

OrthoGain works faster due to direct exosome-mediated cellular communication — lower inflammation, better patient comfort and quicker visible results.

01Reduces inflammation
02Promotes cellular repair
03Enhances collagen synthesis
04Supports cartilage regeneration

Clinical benefits

Faster recovery

From ligament tears, tendon injuries, and fractures.

Reduced pain & inflammation

Without steroid side effects.

Enhanced regeneration

Of muscles, cartilage, and bone.

Improved mobility

And performance, for athletes and active patients.

Autologous safety

No rejection or allergy risk.

Clinical applications

Sports injuries & orthopaedic conditions

Sports Injuries

  • ACL & MCL ligament tears
  • Meniscus injuries
  • Muscle strains & microtears
  • Rotator cuff injuries
  • Tendon & ligament sprains

Orthopaedic Conditions

  • Osteoarthritis (knee, hip, shoulder)
  • Chronic tendinopathies (tennis elbow, Achilles tendonitis, plantar fasciitis)
  • Bone fractures (accelerated healing & mineralization)
  • Cartilage degeneration
  • Post-surgical orthopaedic recovery

Chairside preparation

How to prepare OrthoGain

Six steps, from venous draw to filtered autologous product.

OrthoGain preparation: 1 Blood collection and platelet activation with 30 minute wait, 2 Primary centrifugation 3500 RPM for 10 minutes, 3 Plasma separation, 4 Secondary centrifugation 3500 RPM for 10 minutes, 5 Supernatant plasma collection, 6 Filtration

Head to head

OrthoGain vs PRP / GFC

ParametersPRPGFCEXOS-GFC
Composition Platelets with plasma Platelet-derived growth factors Autologous exosomes + growth factors
Mechanism Indirect GF release Direct GF delivery Direct cellular communication + potent regenerative signaling
Regenerative capacity Moderate Improved Superior — targets inflammation and stimulates true regeneration
Purity Contains RBCs/WBCs Contains cell debris RBC-free, cell-free, highly purified exosomes
Onset of results 4–6 weeks 2–3 weeks 1–2 weeks

Nanoparticle Tracking Analysis (NTA)

Exosome quantification

Nanoparticle Tracking Analysis is a technique used to measure the size distribution and concentration of nanoparticles, including exosomes. NTA combines the principles of laser light scattering and Brownian motion to provide detailed insight into exosome populations.

NTA assay results: particle concentration by size, and intensity by size scatter plot

Particle Concentration

2.05e+13 particles/ml
Original exosome concentration.

Size Distribution

85.7% of particles between 30–150 nm, with a therapeutic peak at 100 nm.

Purity

>98% exosome and growth factor content with negligible impurities. NTA demonstrates excellent batch consistency, ensuring predictable regenerative outcomes.

OrthoGain EXOS-GFC kit — autologous platelet derived growth factor concentrate with exosomes

What ships

OrthoGain kit contains

  • OrthoGain Tubes2 × 5 ml
  • Plasma Collection Tube (sterile)2 × 10 ml
  • Syringe3 × 10 ml
  • Filter1 piece
  • Mfg. Lic. No.MFG/MD/2025/000469

CDSCO Approved Approved by the Central Drugs Standard Control Organisation, India.

Get in touch

Request information

For orthopaedic surgeons, sports medicine physicians, hospitals and distribution partners. Tell us about your practice and we will send pricing, the full protocol and training details.

Kamal Encon Industries Limited
Plot No. 917, Sector-68, IMT Faridabad – 121001
Haryana, India

+91 99711 66553  ·  +91 80762 87050
info@kamalmedtech.com

Sweden office
Kamal Encon Psilox AB, Vallvägen 4A, S75651, Uppsala, Sweden

* Required. We reply to enquiries within one working day.

OrthoGain™ is an autologous, single-patient-use regenerative kit intended for administration by qualified healthcare professionals. Product information on this page is directed at clinicians and is not a substitute for the Instructions for Use. Clinical outcomes vary between patients.